Resources

Poster

Smart Decision Making in Pharmaceutical Development Leveraging Automated Platforms

Automation can benefit pharmaceutical development by enabling the accelerated assessment of the physico-chemical characteristics of investigational new drugs utilizing high-throughput screens. Two...

Read More

Poster

Targeted peptide quantification with small foot-print capillary LC-MS/MS

Quantification of low-abundance proteins remains a challenge for proteomics research. Standard LC-MS/MS often lacks the sensitivity to detect the crucial players in pathways, cellular processes, or...

Read More

Poster

Interfacing Compact to Mass Spec

The compact, portable Axcend Focus LC (Axcend, Provo, UT, USA) comes equipped with either an on-capillary or miniature flow-cell UV-absorbance detector and is suitable for in-field applications as an...

Read More

App Note

Determination of Triazine Herbicides in Aqueous Samples by Capillary HPLC-MS/MS

The compact Axcend Focus LC® was coupled to a relatively small footprint Agilent Ultivo triple quadrupole mass spectrometer for the analysis of triazine pesticides in aqueous samples. Components of a...

Read More

App Note

Determination of Opioids by Capillary HPLC-MS/MS

Abstract This application note demonstrates the use of the compact Axcend Focus LC® capillary chromatograph coupled to an Agilent Ultivo triple quadrupole mass spectrometer for quantitative analysis...

Read More

App Note

Analysis of Biocides Using Compact HPLC

The Axcend Focus LC® (a compact capillary liquid chromatograph) has been successfully used for quantitative analysis of two representative biocides: 4,5-dichloro-2-n-octylisothiazolin-3-one (DCOIT)...

Read More

App Note

Point-of-Care Monitoring for Drugs of Abuse

This application note demonstrates the use of the Axcend Focus LC® (AFLC) for point-of-care analysis of drugs of abuse in clinical settings such as treatment facilities and pain clinics. Traditional...

Read More

Portable Capillary LC for In-Line UV Monitoring and MS Detection: Comparable Sensitivity and Much...

Abstract Pharmaceutical development currently relies on quality separation methods from early discovery through to line-of-site manufacturing. There have been significant advancements made regarding...

Read More

Column Selection Considerations in Compact Capillary Liquid Chromatography

Abstract Recent years have seen significant advances in compact, portable capillary LC instrumentation. This study explores the performances of several commercially available columns within the...

Read More

App Note

Environmentally Friendly Method for the Analysis of Caffeine and Benzoic Acid in Soft Drinks

A simple analysis of caffeine and benzoic acid in soft drinks using the compact Axcend Focus LC® is demonstrated. Linear regression of the calibration data gave R2 values of 0.9993 and 0.9998 for...

Read More

Exploring Biopharmaceutical Analysis with Compact Capillary Liquid Chromatography Instrumentation

A recent trend in the design of liquid chromatography (LC) instrumentation is the move towards miniaturized and portable systems. These smaller platforms provide wider flexibility in operation, with...

Read More

Video

Video: Axcend History

Read More