Innovative High-Performance Liquid Chromatography
Make HPLC Anywhere® a reality with the Axcend Focus LC® — a shoebox-sized, hand-portable, capillary HPLC that breaks the mold for traditional high-performance liquid chromatography systems.
HPLC Anywhere
Axcend
Focus LC®
Axcend’s® Axcend Focus LC® is a breakthrough, fully portable, high-performance liquid chromatography system that can be hand-carried anywhere and used on-the-spot: within a laboratory, inside a glove box, on a scientist’s desk, on a manufacturing line, and yes, even in the field.
A Variety of Advantages
Compact.
Compact.
The Axcend Focus LC® is unique amongst LC products with a small footprint and a battery. In fact, it takes up 1/5 of the benchspace as compared to traditional HPLCs! Key features:
- It is completely self-contained with battery, pump, solvents, waste, column, and detector all inside the case.
- The handle allows it to be easily moved around a lab, to other buildings, or in the field.
- Our iOS application allows the use of a tablet, laptop, or iPhone to run the system
- The Axcend Focus fits in a hood, automation bench, or other synthetic/robotic platform
- Data is available to the scientist immediately-no waiting for results from a central lab or walk-up LC
Portable.
Portable.
The Axcend Focus LC® is the only LC that includes a convenient carrying handle and a battery for remote operation. The idea originated with Dr. Milton Lee at BYU and came to fruition with the founding of Axcend. Key benefits include:
- Hemp/Cannabis-Test Cannabis and Hemp BEFORE harvesting to reach maximum potency and crop value.
- Citrus Beverages-Test Citrus Fruit BEFORE harvesting to determine levels of Limonin.
- Public Safety-Bring Focus to a Hazardous Waste Spill or Clandestine Lab.
- Proteomics Core Labs-Develop the LC separation then bring the LC to the MS Lab with the method, column, and solvent systems pre-loaded.
- Fuel Tank Testing seeking if there are counterfeit fuels and check tracer levels right on the spot.
Green.
Green.
The Axcend Focus LC® nano pumping system and on-column detector requires very small qunatities of sample and mobile phase solvents for analysis lending it to be GREEN by default. Green chemistry, also called sustainable chemistry, is an area of chemistry and chemical engineering focused on the design of products and processes that minimize or eliminate the use and generation of hazardous substances. With flow rates of 0.5-1 mL/minute, a typical HPLC consumes copious amounts of organic solvents. The Axcend Focus LC® weighs less than 8 kg and consumes less than 1.5 mL’s of solvent in a 24-hour period! Key benefits include:
- It is completely self-contained so there is no exposure to the user of the environment. There is no need for a fume hood.
- It uses 1,000 times less solvent then traditional systems.
- It produces minuscule amounts of waste saving money and the environment.
Pharmaceutical.
Pharmaceutical.
The use of Process Analytical Technology (PAT) is of increasing importance to the rapid deployment of Vaccines, Medicines, and other Healthcare Products. The Axcend Focus LC® is the perfect tool that allows scientists to get immediate feedback on the state of an experiment, a manufacturing run, or any other reaction that requires monitoring of reactants and products. Data is collected in real-time allowing the scientist to make better decisions more quickly lowering time-to-market, cost of R&D, and cost of manufacturing.
The Axcend Focus LC® fits in the most compact locations and can be interfaced with automated sample introduction technologies and can be easily transported to locations for critical in-process measurements. Its low solvent usage also allows it to go right in the pilot plant or on the manufacturing floor for inline or at-line measurements. The Axcend Focus LC® High-Performance Liquid Chromatography system (HPLC) delivers repeatable analyses of Active Pharmaceutical Ingredient (API) dissolution.
Click below to learn about the Axcend Focus LC's repeatable analyses of Active Pharmaceutical Ingredient (API) dissolution.
Educational.
Educational.
The American Chemical Society Handbook for Undergraduate Professional Education in Chemistry documents guidelines and evaluation procedures for bachelor degree programs. Specifically “The laboratory experience must include hands-on experience with modern instrumentation such as that listed in section 4.2.” In addition, instruments from at least four of the following five categories must be on-site and used by undergraduates:
- Optical molecular spectroscopy (e.g., FT-IR, fluorescence, Raman, UV-Vis)
- Optical atomic spectroscopy (e.g., atomic absorption, ICP-atomic
- Mass spectrometry (e.g., MS, GC-MS, LC-MS)
- Chromatography and separations (e.g., GC, GPC, HPLC, ion chromatography, capillary electrophoresis, SEC)
- Electrochemistry (e.g., potentiometry, amperometry, coulometry, voltammetry)
Click on the chromatogram below to learn more about the AFLC as a Teaching Tool.
Click below for the PPT Deck on the advantages of the AFLC in the Classroom
Miniaturization of an HPLC enables analytical determination at the point-of-need, whether within a conventional laboratory setting, within a processing facility, or classroom and Laboratory setting. Additionally, it addresses many of the challenges listed above by providing a fully self-contained compact and portable HPLC with capillary flow rates. The Axcend focus LC would satisfy the ACS requirements for an HPLC while providing a cost-effective chromatographic instrument. Challenges in providing instrumentation for modern analytical chemistry courses and undergraduate laboratories include:
- Instrument mobility, and Instrument accessibility and sharing
- Individualized assignments and projects requiring unique instrument methodologies
- Ease of use for both the operator and instructor
- Operating cost (solvent consumption) and Environmental impact
- Limited Bench Space
- Set up and equilibration time.
- Health and safety concerns with exposure to large solvent volumes and large groups of students gathering around instruments.
Petrochemical.
Petrochemical.
The Axcend Focus LC® offers a variety of advantages to the Petrochemical Industry including:
- Analysis of Process Water directly at the holding tank on Oil Platforms with no danger from flammable solvents or other potential hazards
- BTEX analysis from soil, water, or other matrices down to the high PPB range anywhere you need it. At the rig, in the lab, at a spill site…
- Polyaromatic Hydrocarbon (PAH) analysis across a range of matrices and detection limits at point-of-need.
The Axcend Focus LC® fits into almost any compact and remote location allowing it to easily be transported to formerly difficult to reach sites. Its ability to operate on a battery makes it possible to analyze samples when wall power is not available.
Click on the chromatogram below to see more about BTEX performance.
This application note shows how low levels of benzene, toluene, ethyl benzene, and xylenes (BTEX) can be determined in water with the use of relatively large injection volumes. The standard injection valve typically delivers a 40 nL injection volume. Substituting this small internal sample loop valve with a larger external loop enables injections of a wide range of sample volumes from 200 nL and higher.
Compact.
Compact.
The Axcend Focus LC® is unique amongst LC products with a small footprint and a battery. In fact, it takes up 1/5 of the benchspace as compared to traditional HPLCs! Key features:
- It is completely self-contained with battery, pump, solvents, waste, column, and detector all inside the case.
- The handle allows it to be easily moved around a lab, to other buildings, or in the field.
- Our iOS application allows the use of a tablet, laptop, or iPhone to run the system
- The Axcend Focus fits in a hood, automation bench, or other synthetic/robotic platform
- Data is available to the scientist immediately-no waiting for results from a central lab or walk-up LC
Portable.
Portable.
The Axcend Focus LC® is the only LC that includes a convenient carrying handle and a battery for remote operation. The idea originated with Dr. Milton Lee at BYU and came to fruition with the founding of Axcend. Key benefits include:
- Hemp/Cannabis-Test Cannabis and Hemp BEFORE harvesting to reach maximum potency and crop value.
- Citrus Beverages-Test Citrus Fruit BEFORE harvesting to determine levels of Limonin.
- Public Safety-Bring Focus to a Hazardous Waste Spill or Clandestine Lab.
- Proteomics Core Labs-Develop the LC separation then bring the LC to the MS Lab with the method, column, and solvent systems pre-loaded.
- Fuel Tank Testing seeking if there are counterfeit fuels and check tracer levels right on the spot.
Green.
Green.
The Axcend Focus LC® nano pumping system and on-column detector requires very small qunatities of sample and mobile phase solvents for analysis lending it to be GREEN by default. Green chemistry, also called sustainable chemistry, is an area of chemistry and chemical engineering focused on the design of products and processes that minimize or eliminate the use and generation of hazardous substances. With flow rates of 0.5-1 mL/minute, a typical HPLC consumes copious amounts of organic solvents. The Axcend Focus LC® weighs less than 8 kg and consumes less than 1.5 mL’s of solvent in a 24-hour period! Key benefits include:
- It is completely self-contained so there is no exposure to the user of the environment. There is no need for a fume hood.
- It uses 1,000 times less solvent then traditional systems.
- It produces minuscule amounts of waste saving money and the environment.
Pharmaceutical.
Pharmaceutical.
The use of Process Analytical Technology (PAT) is of increasing importance to the rapid deployment of Vaccines, Medicines, and other Healthcare Products. The Axcend Focus LC® is the perfect tool that allows scientists to get immediate feedback on the state of an experiment, a manufacturing run, or any other reaction that requires monitoring of reactants and products. Data is collected in real-time allowing the scientist to make better decisions more quickly lowering time-to-market, cost of R&D, and cost of manufacturing.
The Axcend Focus LC® fits in the most compact locations and can be interfaced with automated sample introduction technologies and can be easily transported to locations for critical in-process measurements. Its low solvent usage also allows it to go right in the pilot plant or on the manufacturing floor for inline or at-line measurements. The Axcend Focus LC® High-Performance Liquid Chromatography system (HPLC) delivers repeatable analyses of Active Pharmaceutical Ingredient (API) dissolution.
Click below to learn about the Axcend Focus LC's repeatable analyses of Active Pharmaceutical Ingredient (API) dissolution.
Educational.
Educational.
The American Chemical Society Handbook for Undergraduate Professional Education in Chemistry documents guidelines and evaluation procedures for bachelor degree programs. Specifically “The laboratory experience must include hands-on experience with modern instrumentation such as that listed in section 4.2.” In addition, instruments from at least four of the following five categories must be on-site and used by undergraduates:
- Optical molecular spectroscopy (e.g., FT-IR, fluorescence, Raman, UV-Vis)
- Optical atomic spectroscopy (e.g., atomic absorption, ICP-atomic
- Mass spectrometry (e.g., MS, GC-MS, LC-MS)
- Chromatography and separations (e.g., GC, GPC, HPLC, ion chromatography, capillary electrophoresis, SEC)
- Electrochemistry (e.g., potentiometry, amperometry, coulometry, voltammetry)
Click on the chromatogram below to learn more about the AFLC as a Teaching Tool.
Click below for the PPT Deck on the advantages of the AFLC in the Classroom
Miniaturization of an HPLC enables analytical determination at the point-of-need, whether within a conventional laboratory setting, within a processing facility, or classroom and Laboratory setting. Additionally, it addresses many of the challenges listed above by providing a fully self-contained compact and portable HPLC with capillary flow rates. The Axcend focus LC would satisfy the ACS requirements for an HPLC while providing a cost-effective chromatographic instrument. Challenges in providing instrumentation for modern analytical chemistry courses and undergraduate laboratories include:
- Instrument mobility, and Instrument accessibility and sharing
- Individualized assignments and projects requiring unique instrument methodologies
- Ease of use for both the operator and instructor
- Operating cost (solvent consumption) and Environmental impact
- Limited Bench Space
- Set up and equilibration time.
- Health and safety concerns with exposure to large solvent volumes and large groups of students gathering around instruments.
Petrochemical.
Petrochemical.
The Axcend Focus LC® offers a variety of advantages to the Petrochemical Industry including:
- Analysis of Process Water directly at the holding tank on Oil Platforms with no danger from flammable solvents or other potential hazards
- BTEX analysis from soil, water, or other matrices down to the high PPB range anywhere you need it. At the rig, in the lab, at a spill site…
- Polyaromatic Hydrocarbon (PAH) analysis across a range of matrices and detection limits at point-of-need.
The Axcend Focus LC® fits into almost any compact and remote location allowing it to easily be transported to formerly difficult to reach sites. Its ability to operate on a battery makes it possible to analyze samples when wall power is not available.
Click on the chromatogram below to see more about BTEX performance.
This application note shows how low levels of benzene, toluene, ethyl benzene, and xylenes (BTEX) can be determined in water with the use of relatively large injection volumes. The standard injection valve typically delivers a 40 nL injection volume. Substituting this small internal sample loop valve with a larger external loop enables injections of a wide range of sample volumes from 200 nL and higher.
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