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Targeted peptide quantification with small foot-print capillary LC-MS/MS
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Come see us at HPLC! Table 9
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Axcend® announces the launch of its small footprint, full-stack chromatography system.
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Mass spectrometry is often the limiting factor in detecting low-abundance analytes. But what if...Read More
Featured Resources
Size exclusion chromatography (SEC) is a technique often used to resolve large molecules based off...Read More
App Note
Capillary-Scale Size Exclusion Chromatography Using the Axcend Focus LC®
Size exclusion chromatography (SEC) is a technique often used to resolve large molecules based off their hydrodynamic radius (or size). This technique is widely used for the analysis of...
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App Note
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Analysis of Benzodiazepines Using Portable LC-MS Instrumentation
Mass spectrometry (MS) is a powerful detection method that provides high sensitivity and structural information of an analyte. Liquid chromatography (LC) is commonly used as a separation technique...
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On-Line Monitoring of a Heterogenous Reaction Using the Axcend InFocus™ Automated Sampler and...
On-line sampling and analysis of heterogenous reaction mixtures is a critical application of modern process analytical technology (PAT). This application note describes the monitoring of a...
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Assessing Ibuprofen in Mini-Tablets Using the Axcend Focus LC® Micro-HPLC-UV System
This study compares two analytical methods—UV spectrophotometry and micro-HPLC-UV—for quantifying ibuprofen content in pediatric mini-tablets. While both methods demonstrated acceptable linearity,...
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Low Flow Direct Infusion Mass Spectrometry Using AutoFocus™
Direct infusion mass spectrometry is a common technique for screening for both qualitative and quantitative analysis. In many direct infusion setups, samples are manually loaded into a syringe before...
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MDA Quantification in Jet Fuel
ASTM D1655, Standard Specification for Aviation Turbine Fuels, defines a maximum allowable limit for Metal Deactivator Additive (MDA) in jet fuel. ASTM D8545 is currently the only ASTM-published...
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Adapting Pharmaceutical Monographs for Capillary Scale HPLC Using USP 621 Guidelines
Abstract Compact capillary scale liquid chromatography (LC) instrumentation offers a platform for high performance separations with considerable reduction in solvent consumption, operating cost, and...
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Small-Footprint Capillary UHPLC/MS Technology Significantly Reducing Consumption of PFAS Containing...
Poster Reprint ASMS 2025 Poster number MP 230 Introduction Synthetic oligonucleotides are important biotherapeutic drugs because of their broad applications in genetic research, drug development,...
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Validating Repeatability Performance of the Axcend Focus LC®: Single- and Multi-Day Study
Abstract Innovative tools that purport to improve workflows through saving time, space, or cost must also provide analytical results that are nominally the same or better than incumbent technologies....
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Determination of Pharmaceuticals by Capillary HPLC-MS/MS
Abstract This application note demonstrates the use of a compact portable capillary liquid chromatograph, the Axcend Focus LC, coupled to an Agilent Ultivo triple quadrupole mass spectrometer for...
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Determination of Triazine Herbicides in Aqueous Samples by Capillary HPLC-MS/MS
The compact Axcend Focus LC® was coupled to a relatively small footprint Agilent Ultivo triple quadrupole mass spectrometer for the analysis of triazine pesticides in aqueous samples. Components of a...
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Determination of Opioids by Capillary HPLC-MS/MS
Abstract This application note demonstrates the use of the compact Axcend Focus LC® capillary chromatograph coupled to an Agilent Ultivo triple quadrupole mass spectrometer for quantitative analysis...
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ISCC & GC×GC Symposium
May 17-22, 2026
Find us at Riva 2026, the combined 44th International Symposium on Capillary Chromatography and...
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