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Targeted peptide quantification with small foot-print capillary LC-MS/MS
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Axcend® announces the launch of its small footprint, full-stack chromatography system.
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Mass spectrometry is often the limiting factor in detecting low-abundance analytes. But what if...Read More
Featured Resources
Size exclusion chromatography (SEC) is a technique often used to resolve large molecules based off...Read More
Webinar
Understanding Capillary LC - Part 6: Unlocking LC-MS Sensitivity
April 21, 2026
Mass spectrometry is often the limiting factor in detecting low-abundance analytes. But what if your LC could help you see more before the signal even reaches the MS? In this sixth installment of the...
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App Note
Capillary-Scale Size Exclusion Chromatography Using the Axcend Focus LC®
Size exclusion chromatography (SEC) is a technique often used to resolve large molecules based off their hydrodynamic radius (or size). This technique is widely used for the analysis of...
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On-Line Monitoring of a Heterogenous Reaction Using the Axcend InFocus™ Automated Sampler and...
On-line sampling and analysis of heterogenous reaction mixtures is a critical application of modern process analytical technology (PAT). This application note describes the monitoring of a...
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Understanding Capillary LC - Part 5: Detectors, Sensitivity and MS-UV
February 18, 2026
Detection is one of the most critical—and often misunderstood—elements of capillary liquid chromatography. In this fifth installment of the Understanding Capillary LC lecture series, Dr. Sam Foster...
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Understanding Capillary LC - Part 4: Reducing Extra Column Effects
December 10, 2025
The fluidic pathway plays a critical role in achieving high-resolution separations at the capillary scale. In this fourth installment of Understanding Capillary LC, Dr. Sam Foster explores how...
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Assessing Ibuprofen in Mini-Tablets Using the Axcend Focus LC® Micro-HPLC-UV System
This study compares two analytical methods—UV spectrophotometry and micro-HPLC-UV—for quantifying ibuprofen content in pediatric mini-tablets. While both methods demonstrated acceptable linearity,...
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Understanding Capillary LC - Part 3: Choosing the Right Column
October 15, 2025
The column is the heart of any liquid chromatography system, and at the capillary scale, the right choice can make or break your separation. In the third installment of our Understanding Capillary LC...
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Understanding Capillary LC - Part 2: Solvent Delivery Systems
August 20, 2025
Solvent delivery is a critical component of any liquid chromatography system, and at the capillary scale, the choice of pumping mechanism can make or break performance. In the second installment of...
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Understanding Capillary LC - Part 1: Intro to Scale, Flow and Fit
July 25, 2025
Capillary-scale liquid chromatography (capillary LC) is reshaping how scientists think about separation performance, solvent consumption, and instrument design. But what exactly defines...
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Immersion Probe Raman for Pharmaceutical Suspension Testing in the Manufacturing Plant and...
Abstract Traditional analysis of pharmaceutical suspensions by liquid chromatography requires time, manual sample preparation, and solvents. In this work, we explored an alternative procedure for...
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Adapting Pharmaceutical Monographs for Capillary Scale HPLC Using USP 621 Guidelines
Abstract Compact capillary scale liquid chromatography (LC) instrumentation offers a platform for high performance separations with considerable reduction in solvent consumption, operating cost, and...
Read MorePoster
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Micro-HPLC-UV Method for Assessing Ibuprofen Content in Pediatric Mini-Tablets and Identification...
Introduction Age-appropriate pharmaceutical formulations are crucial for ensuring safe and effective drug administration. Mini-tablets (2 mm, 10 mg, Figure 1a and 1b) offer a promising solution in...
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ISCC & GC×GC Symposium
May 17-22, 2026
Find us at Riva 2026, the combined 44th International Symposium on Capillary Chromatography and...
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