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Meet the Axcend

Focus LC®

Reliable Results Delivered Anywhere Your Teams Work

With the smallest footprint in HPLC technology, the Focus LC delivers the reliable and repeatable results that your teams need, wherever they work—from the field to the lab to the hood.

What Makes Focus LC Unique?

The flexibility that the Axcend Focus LC brings to your workflow means you can integrate it seamlessly into your processes for industry-leading accuracy and reliability. So, bring the lab to the sample—and use far less of the sample for real-time results than legacy big box systems require.

AFLC 1 - Full Stack in Lab

Robust and Capable

Get the accurate analysis you need with more real-time results from every drop of your sample.

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Compact Design

At only 18 pounds, the Focus LC is lightweight enough to bring the lab to the sample wherever your teams work.

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Low Cost of Ownership

Use 500-100 times less solvent than the legacy big box system for less waste, lower energy costs, and less maintenance.

Real World Success Stories

The Axcend Focus LC is a powerful tool that allows us to monitor critical data in real time at the point of production.

Ashley Matthews

Director of Quality
Vestaron
The size of the instrument, ease-of-use and low price point give our students practical experience and exposure to the chromatography challenges they’ll face in the workplace. The Axcend Focus LC is the right choice for inexperienced users because it’s hard to break.

Dr. Clinton King

Organic Chemistry Lab Manager
Utah Valley University

Experience chromatography without limits

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Key Features & Specs

Precision Engineered for Maximum Impact

Easily bring the lab to the sample or use the Focus LC in a state-of-the-art laboratory thanks to the smallest footprint in the industry. With lower solvent consumption, reduced waste, and less energy use, you'll benefit from both reliability and efficiency wherever your teams work.

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Compact, Lightweight and Powerful

At 18 pounds and operating up to 10,000 psi, the Focus LC provides improved sensitivity and reduced on-column sample dilution.
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Take the Lab to the Sample™

Deliver real-time results in the lab, in the field, or anywhere else that legacy big box systems can't reach.
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Integration Is Easy and Painless

The Focus LC makes integration simpler, including low volume interfacing kits for connections to MS and photodiode array (PDA) UV detection.
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The Column Choice is Yours

Operate the Focus LC using any standard capillary HPLC or UHPLC column, allowing you to compare results to your existing LC.
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Lowest Cost of Ownership

Benefit from solvent and waste costs that are about 1/1000th of analytical-scale systems, with the Focus LC paying for itself in as little as two years.
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The Most Eco-Friendly HPLC

Use under 10 mL per week of solvents with a fraction of the energy consumption required by legacy big box LCs.
Focus LC Accessories

Customize Your Axcend Focus LC® with These Options

The Focus LC supports a wide range of HPLC columns including single or dual configurations with multiple stationary phases to accommodate diverse analytical needs. Easily connect third-party columns to tailor separations for specific analytes or workflows without sacrificing performance or compatibility.

Choose from Fixed Column Cartridges for routine assays or Heated Column Cartridges for temperature-sensitive methods. Both offer low sample volumes, reduced solvent use, and single or dual UV detection at 235, 255, or 275 nm.

Whether you're working at the bench or in a production environment, the Focus LC offers versatile sample introduction options. Use manual injection, integrate with AutoFocus for unattended automated workflows, or pair with InFocus to enable in-line process analytical technology (PAT). The result: reduced hands-on time, better consistency, and faster decision-making.

The Focus LC seamlessly integrates with leading chromatography data systems, including Agilent OpenLab, Waters Empower, and DataApex Clarity. Prefer a streamlined approach? Use Axcend Drive—our intuitive, browser-based interface that gives you full control without the overhead of complex installations.

expand your focus

Build the System that Works for You

AutoFocus (w label)

AutoFocus

Automate your sample injection for repeatable results and low carry-over.

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InFocus (w label)

InFocus

Access more precise reaction monitoring with our real-time PAT system.

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FocusArray (w label)

FocusArray

Improve your detection sensitivity with the smallest DAD for capillary HPLC.

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Trusted Results.
New Possibilities.

Experience Axcend technology firsthand and see how the fastest real-time monitoring and smallest footprint in the industry can make an impact on your workflow.

Industry Applications

Broad Range of Uses

The flexibility and reliability of the Focus LC allow you to use the system to tackle nearly any analytical chemistry challenge. Browse some recent examples below.