Interfacing Compact to Mass Spec

The compact, portable Axcend Focus LC (Axcend, Provo, UT, USA) comes equipped with either an on-capillary or miniature flow-cell UV-absorbance detector and is suitable for in-field applications as an autonomous instrument.1,2 It can also be used in a laboratory setting as a stationary compact liquid chromatograph (LC). In the latter case, the sensitivity and identification capabilities of the instrument can be enhanced by interfacing it with a suitable mass spectrometer (MS). In this work, we interfaced an Axcend Focus LC to an Agilent Ultivo, which is among the smallest footprint commercially available triple quadrupole mass spectrometers.

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