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Our resources accessed from the list below give a flavor of the variety of liquid chromatography analyses that can be addressed using the Axcend Focus LC®.

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App Note

Capillary-Scale Radiopharmaceutical Analysis using the Axcend Focus LC®

The production and validation of radiopharmaceutical compounds result in generation of radioactive solvent waste. These waste streams must be stored for a sufficient time to allow for decay to occur...

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App Note

Capillary-Scale Analysis of Nontoxic Antibody Drug Conjugate (ADC) Mimics

Antibody drug conjugates (ADCs) belong to a class of drugs featuring a monoclonal antibody conjugated to a toxic payload. The antibody allows for the delivery of this payload to specific antigen...

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Webinar

Understanding Capillary LC - Part 6: Unlocking LC-MS Sensitivity

April 21, 2026

Mass spectrometry is often the limiting factor in detecting low-abundance analytes. But what if your LC could help you see more before the signal even reaches the MS? In this sixth installment of the...

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App Note

Capillary-Scale Size Exclusion Chromatography Using the Axcend Focus LC®

Size exclusion chromatography (SEC) is a technique often used to resolve large molecules based off their hydrodynamic radius (or size). This technique is widely used for the analysis of...

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App Note

Analysis of Benzodiazepines Using Portable LC-MS Instrumentation

Mass spectrometry (MS) is a powerful detection method that provides high sensitivity and structural information of an analyte. Liquid chromatography (LC) is commonly used as a separation technique...

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App Note

On-Line Monitoring of a Heterogenous Reaction Using the Axcend InFocus™ Automated Sampler and...

On-line sampling and analysis of heterogenous reaction mixtures is a critical application of modern process analytical technology (PAT). This application note describes the monitoring of a...

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Webinar

Understanding Capillary LC - Part 5: Detectors, Sensitivity and MS-UV

February 18, 2026

Detection is one of the most critical—and often misunderstood—elements of capillary liquid chromatography. In this fifth installment of the Understanding Capillary LC lecture series, Dr. Sam Foster...

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Webinar

Understanding Capillary LC - Part 4: Reducing Extra Column Effects

December 10, 2025

The fluidic pathway plays a critical role in achieving high-resolution separations at the capillary scale. In this fourth installment of Understanding Capillary LC, Dr. Sam Foster explores how...

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Webinar
Webinar snapshot showing a comparison of analytical scale and capillary scale liquid chromatography for a USP monograph of hydrochlorothiazide.

Adapting HPLC to the Capillary Scale: Insights from Academia and Industry

November 3, 2025

Learn how scientists are adapting analytical high-performance liquid chromatography (HPLC) methods to the capillary scale—cutting solvent use, improving sensitivity, and adapting validated...

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App Note

Assessing Ibuprofen in Mini-Tablets Using the Axcend Focus LC® Micro-HPLC-UV System

This study compares two analytical methods—UV spectrophotometry and micro-HPLC-UV—for quantifying ibuprofen content in pediatric mini-tablets. While both methods demonstrated acceptable linearity,...

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Webinar

Understanding Capillary LC - Part 3: Choosing the Right Column

October 15, 2025

The column is the heart of any liquid chromatography system, and at the capillary scale, the right choice can make or break your separation. In the third installment of our Understanding Capillary LC...

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App Note

Low Flow Direct Infusion Mass Spectrometry Using AutoFocus™

Direct infusion mass spectrometry is a common technique for screening for both qualitative and quantitative analysis. In many direct infusion setups, samples are manually loaded into a syringe before...

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AAPS PharmSci360

October 25-28, 2026

Join us at AAPS PharmSci360! AAPS is the convener of the pharmaceutical science community, bringing...

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Eastern Analytical Symposium

November 16-18, 2026

Find us at this year's Eastern Analytical Symposium (EAS)! EAS has been the leading conference in...

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