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Targeted peptide quantification with small foot-print capillary LC-MS/MS
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Come see us at HPLC! Table 9
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Axcend® announces the launch of its small footprint, full-stack chromatography system.
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Mass spectrometry is often the limiting factor in detecting low-abundance analytes. But what if...Read More
Featured Resources
Size exclusion chromatography (SEC) is a technique often used to resolve large molecules based off...Read More
Immersion Probe Raman for Pharmaceutical Suspension Testing in the Manufacturing Plant and...
Abstract Traditional analysis of pharmaceutical suspensions by liquid chromatography requires time, manual sample preparation, and solvents. In this work, we explored an alternative procedure for...
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App Note
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Adapting Pharmaceutical Monographs for Capillary Scale HPLC Using USP 621 Guidelines
Abstract Compact capillary scale liquid chromatography (LC) instrumentation offers a platform for high performance separations with considerable reduction in solvent consumption, operating cost, and...
Read MorePoster
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Micro-HPLC-UV Method for Assessing Ibuprofen Content in Pediatric Mini-Tablets and Identification...
Introduction Age-appropriate pharmaceutical formulations are crucial for ensuring safe and effective drug administration. Mini-tablets (2 mm, 10 mg, Figure 1a and 1b) offer a promising solution in...
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Reducing PFAS in Oligonucleotide Analysis: A New Path Forward
June 24, 2025
Synthetic oligonucleotides are increasingly central to modern research and therapeutic development. But their analysis via LC/MS often relies on large volumes of hazardous mobile phase additives like...
Read MorePoster
New Compact Sampling and Sample Preparation Technologies for Portable Capillary Liquid...
High performance liquid chromatography (HPLC) is one of the most used analytical techniques in the world. Traditional analytical scale instrumentation consumes ~50 L of solvent per year, with a...
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Small-Footprint Capillary UHPLC/MS Technology Significantly Reducing Consumption of PFAS Containing...
Poster Reprint ASMS 2025 Poster number MP 230 Introduction Synthetic oligonucleotides are important biotherapeutic drugs because of their broad applications in genetic research, drug development,...
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Save Solvent and Samples with Compact Capillary Scale LC
May 15, 2025
Capillary scale liquid chromatography offers separations comparable to the more traditional analytical scale at a fraction of the solvent consumption. Herein we describe a compact capillary scale LC...
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Validating Repeatability Performance of the Axcend Focus LC®: Single- and Multi-Day Study
Abstract Innovative tools that purport to improve workflows through saving time, space, or cost must also provide analytical results that are nominally the same or better than incumbent technologies....
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Determination of Triazine Herbicides in Aqueous Samples by Capillary HPLC-MS/MS
The compact Axcend Focus LC® was coupled to a relatively small footprint Agilent Ultivo triple quadrupole mass spectrometer for the analysis of triazine pesticides in aqueous samples. Components of a...
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Determination of Opioids by Capillary HPLC-MS/MS
Abstract This application note demonstrates the use of the compact Axcend Focus LC® capillary chromatograph coupled to an Agilent Ultivo triple quadrupole mass spectrometer for quantitative analysis...
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Analysis of Biocides Using Compact HPLC
The Axcend Focus LC® (a compact capillary liquid chromatograph) has been successfully used for quantitative analysis of two representative biocides: 4,5-dichloro-2-n-octylisothiazolin-3-one (DCOIT)...
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Portable Capillary LC for In-Line UV Monitoring and MS Detection: Comparable Sensitivity and Much...
Abstract Pharmaceutical development currently relies on quality separation methods from early discovery through to line-of-site manufacturing. There have been significant advancements made regarding...
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ISCC & GC×GC Symposium
May 17-22, 2026
Find us at Riva 2026, the combined 44th International Symposium on Capillary Chromatography and...
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