HPLC

Find us at HPLC 2025! The HPLC symposium series is known as the world’s leading conference on liquid phase separations and their hyphenation with advanced detection technologies, including mass spectrometry and data treatment. The 2025 conference will have a strong focus on industrial research as well as on the automation of the analytical lab and its data flows. 

Event Details

DATES: June 15-19, 2025

LOCATION: Bruges, Belgium

BOOTH: 23

Our Presentations

Be sure to attend our presentations throughout the conference to hear the latest data and insights from our experts and collaborators.

New Compact Sampling and Sample Preparation Technologies for Portable Capillary Liquid Chromatography to Meet Today’s Evolving Needs

POSTER | June 17, 2025 | 1:15 - 3:50 PM | Board SAP-14 | Cary Simpson, VP, Axcend

The adoption of liquid chromatography (LC) for a variety of routine but challenging applications such as on-line analysis and reaction monitoring has been limited by instrument size and unacceptable consumption and disposal of organic solvents precluding co-location with associated sampling and sample preparation equipment. The use of compact instrumentation is obvious to improve integration between sampling and LC analysis in non-ideal situations as compared to conventional analytical LC on a laboratory bench. To solve these problems, a compact sample preparation module for compact capillary LC was developed to automate sampling, filtration, and analysis from a range of reaction vessels and other on-line sample sources. The associated nontrivial processes of sampling from moving streams, elimination of matrix interferents, concentration of target analytes, and on-line introduction of samples into compact LC at sub-microliter-to-microliter volumes and flow rates (i.e., microliters per minute) will be described and demonstrated for selected real-world monitoring applications. In addition, a new autosampler designed specifically for compactness, portability, and compatibility with compact LC will be described and demonstrated.

On-line Sample Introduction and Detection Methods for Small Footprint Capillary LC

PRESENTATION | June 18, 2025 | 5:55 PM | Foyer, Level 3 | Greg Ward, CEO, Axcend

Small footprint LC addresses rapidly growing interest in (a) minimal laboratory bench space, (b) greatly reduced use of mobile phase, (c) green analytical LC, (d) ease of movement from one spot to another in the laboratory, and (d) ease of interfacing with a variety of detectors (e.g., LEDs of specific wavelengths, diode arrays, mass spectrometry, and radioactivity). While capillary LC instruments have been available for some time, small footprint capillary LC and complementary automated systems for sample preparation and detection have been limited. To address this concern, a compact sample preparation platform for compact capillary LC was developed to automate sampling, filtration, and extraction from a range of liquid sample sources. The associated nontrivial processes of sampling from moving streams, elimination of matrix interferents, concentration of target analytes, and on-line introduction of samples into compact LC at sub-microliter-to-microliter volumes and flow rates (i.e., microliters per minute) will be described and demonstrated for selected applications. In addition, a new autosampler designed specifically for compactness, portability, and compatibility with small footprint, compact LC will be described and demonstrated.

From Our Collaborators: Focus LC in Action

Explore how researchers and industry experts are using Axcend’s small-footprint LC systems in real-world applications. These partner-led presentations highlight innovative approaches made possible by our Focus LC. 

Development and Validation of a Micro-HPLC-UV Method for Assessing Ibuprofen Content in Pediatric Mini-Tablets and Identification of a Process-Related Impurity

POSTER | June 16, 2025 | 1:30 - 4:30 PM | Board PHA-55| Giorgio Marrubini, University of Pavia

Analyzing Complex Samples with Compact Capillary LC

KEYNOTE | June 18, 2025 | 4:30 PM | Foyer, Level 3 | Jim Grinias, Rowan University